I encountered this issue when I deactivated the object of the ostrich spine.
This is the normal display.
After hiding the riding, we got the errors below.
NullReferenceException: Object reference not set to an instance of an object
Spine.Unity.SkeletonGraphic.UpdateMeshMultipleCanvasRenderers (Spine.Unity.SkeletonRendererInstruction currentInstructions, System.Boolean keepRendererCount) (at Assets/ThirdPart/Spine/Runtime/spine-unity/Components/SkeletonGraphic.cs:696)
Spine.Unity.SkeletonGraphic.UpdateMesh (System.Boolean keepRendererCount) (at Assets/ThirdPart/Spine/Runtime/spine-unity/Components/SkeletonGraphic.cs:563)
Spine.Unity.SkeletonGraphic.LateUpdate () (at Assets/ThirdPart/Spine/Runtime/spine-unity/Components/SkeletonGraphic.cs:319)